Category: History of Cardiology

Table 1. Antiplatelet drugs, launch date, and associated trials Drug Name Year Launched in the USA Important Trials Aspirin 1897 ISIS-2, GISSI Clopidogrel 1998 CAPRIE, CURE Ticagrelor 2011 PLATO Prasugrel 2009 TRITON-TIMI-38 Cangrelor 2015 CHAMPION trials Table 2. Antiplatelet drugs and pharmacodynamics Aspirin Clopidogrel Prasugrel Ticagrelor Cangrelor Class COX-Inhibitor Thienopyridine Thienopyridine Cyclopentyl-triazolopyrimidine Non-thienopyridine Receptor Binding…